The burden of substance abuse disorders can fall heavily on the families and friends of those who battle addictions. But society also pays a great deal through increased crime. Treatment programs can reduce those costs. For at least two decades, we’ve known substance use and crime go hand in hand.… Read More »Spend a Dollar on Drug Treatment, and Save More on Crime Reduction
BY KATHY MCLEISH APR 27, 2017 One-third of children who came into the care of the Queensland’s Department of Child Safety in 2016 had parents who use or have used methamphetamines, most commonly ice, a new report has found. About 60 per cent of those 749 children… Read More »‘Ice corridors’ mean one-third of Queensland children in protection have parent using meth
Abstract: The long-lasting effects of gestational cannabinoids exposure on the adult brain of the offspring are still controversial. It has already been shown that pre- or perinatal cannabinoids exposure induces learning and memory disruption in rat adult offspring, associated with permanent alterations of cortical glutamatergic neurotransmission… Read More »Long-lasting alterations of hippocampal GABAergic neurotransmission in adult rats following perinatal Δ9-THC exposure
Nestoros JN1, Vakonaki E2, Tzatzarakis MN2, Alegakis A2, Skondras MD3, Tsatsakis AM2. Author information Abstract BACKGROUND AND OBJECTIVES: The purpose of this study was to evaluate the extent of short-term memory impairment and schizophrenia-like symptoms in heavy and systematic cannabis users and the association between the severity of abuse and the… Read More »Long lasting effects of chronic heavy cannabis abuse
Valdeolivas S1,2,3, Sagredo O4,5,6, Delgado M7,8, Pozo MA9,10, Fernández-Ruiz J11,12,13. Author information Abstract Several cannabinoids afforded neuroprotection in experimental models of Huntington’s disease (HD). We investigated whether a 1:1 combination of botanical extracts enriched in either ∆⁸-tetrahydrocannabinol (∆⁸-THC) or cannabidiol (CBD), which are the main constituents of the cannabis-based… Read More »Effects of a Sativex-Like Combination of Phytocannabinoids on Disease Progression in R6/2 Mice, an Experimental Model of Huntington’s Disease.
Rossignoli MT1, Lopes-Aguiar C2, Ruggiero RN3, Do Val da Silva RA4, Bueno-Junior LS5, Kandratavicius L6, Peixoto-Santos JE7, Crippa JA8, Cecilio Hallak JE9, Zuardi AW10, Szawka RE11, Anselmo-Franci J12, Leite JP13, Romcy-Pereira RN14. Author information Abstract The prefrontal cortex (PFC), amygdala and hippocampus display a coordinated activity during acquisition of associative fear memories. Evidence indicates that PFC engagement in… Read More »Selective post-training time window for memory consolidation interference of cannabidiol into the prefrontal cortex: Reduced dopaminergic modulation and immediate gene expression in limbic circuits.
Naftali T1,2, Mechulam R3,4, Marii A5, Gabay G6,7, Stein A6,7, Bronshtain M6,7, Laish I6,7, Benjaminov F6,7, Konikoff FM6,7. Author information Abstract BACKGROUND: Cannabidiol (CBD) is an anti-inflammatory cannabinoid shown to be beneficial in a mouse model of IBD. Lacking any central effect, cannabidiol is an attractive option for treating inflammatory diseases. AIM: To assess the… Read More »Low-Dose Cannabidiol Is Safe but Not Effective in the Treatment for Crohn’s Disease, a Randomized Controlled Trial.
Deborah S. Hasin, PhD1,2,3; Aaron L. Sarvet, MPH1,2; Magdalena Cerdá, DrPH4; et alKatherine M. Keyes, PhD1,3; Malka Stohl, MS2; Sandro Galea, MD, DrPH5; Melanie M. Wall, PhD1,2,6 JAMA Psychiatry. Published online April 26, 2017. doi:10.1001/jamapsychiatry.2017.0724 Question Are US state medical marijuana laws one of the underlying factors for increases in risk for adult cannabis use and cannabis use disorders seen since the early 1990s? Findings In this analysis… Read More »US Adult Illicit Cannabis Use, Cannabis Use Disorder, and Medical Marijuana Laws1991-1992 to 2012-2013
“It is beyond epidemic proportions. There truly is a tidal wave of Alzheimers disease”, says, Dr. Fortanasce. An estimated 200,000 people in the United States un rage 65 are living with younger onset Alzheimers disease. And hundreds of thousands more are coping with mild cognitive… Read More »Kicking Pot to the Curb: Cannabis and Alzheimer’s?
