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February 2018

Rates and Predictors of Conversion to Schizophrenia or Bipolar Disorder Following Substance-Induced Psychosis

Results: Overall, 32.2% (95% CI=29.7–34.9) of patients with a substance-induced psychosis converted to either bipolar or schizophrenia-spectrum disorders. The highest conversion rate was found for cannabis-induced psychosis, with 47.4% (95% CI=42.7–52.3) converting to either schizophrenia or bipolar disorder. Young age was associated with a higher risk of… Read More »Rates and Predictors of Conversion to Schizophrenia or Bipolar Disorder Following Substance-Induced Psychosis

The Cannabis Paradox

Roger Ladouceur – Canadian Family Physician February 2018 “The evidence indicates the most consistent effects of medical cannabinoids are adverse events. A variety of adverse events have a greater magnitude of effect than the potential benefits for the conditions targeted.1 The conclusions drawn by this analysis… Read More »The Cannabis Paradox

Cannabis does more harm than good: Health officials warn doctors against prescribing the drug for ailments as the effects outweigh the minor benefits

New medical guidelines have been issued in Canada, where cannabis is legal They warn the effects of the drug outweigh minor benefits for most conditions  And for some, it states it most often is only marginally better than a placebo  The new document will be… Read More »Cannabis does more harm than good: Health officials warn doctors against prescribing the drug for ailments as the effects outweigh the minor benefits

Freshman year alcohol and marijuana use prospectively predict time to college graduation and subsequent adult roles and independence

Conclusions These results indicated that greater frequency of freshman year binge drinking and marijuana use is significantly related to delayed college graduation, which supports the importance of pre-college interventions targeted at decreasing heavy drinking and marijuana use. Thus, highlighting the harmful academic outcomes associated with binge… Read More »Freshman year alcohol and marijuana use prospectively predict time to college graduation and subsequent adult roles and independence

Cannabis Users Show Enhanced Expression of CB1-5HT2A Receptor Heteromers in Olfactory Neuroepithelium Cells

Received: 17 August 2017 /Accepted: 8 December 2017 – Springer Nature 2017 Abstract Cannabinoid CB1 receptors (CB1R) and serotonergic 2A receptors (5HT2AR) form heteromers in the brain of mice where theymediate the cognitive deficits produced by delta-9-tetrahydrocannabinol. However, it is still unknown whether the expression… Read More »Cannabis Users Show Enhanced Expression of CB1-5HT2A Receptor Heteromers in Olfactory Neuroepithelium Cells

Cannabis Users Show Enhanced Expression of CB1-5HT2A Receptor Heteromers in Olfactory Neuroepithelium Cells

Received: 17 August 2017 /Accepted: 8 December 2017 – Springer Nature 2017 Abstract Cannabinoid CB1 receptors (CB1R) and serotonergic 2A receptors (5HT2AR) form heteromers in the brain of mice where theymediate the cognitive deficits produced by delta-9-tetrahydrocannabinol. However, it is still unknown whether the expression… Read More »Cannabis Users Show Enhanced Expression of CB1-5HT2A Receptor Heteromers in Olfactory Neuroepithelium Cells

Cannabis Users Show Enhanced Expression of CB1-5HT2A Receptor Heteromers in Olfactory Neuroepithelium Cells

Received: 17 August 2017 /Accepted: 8 December 2017 – Springer Nature 2017 Abstract Cannabinoid CB1 receptors (CB1R) and serotonergic 2A receptors (5HT2AR) form heteromers in the brain of mice where theymediate the cognitive deficits produced by delta-9-tetrahydrocannabinol. However, it is still unknown whether the expression… Read More »Cannabis Users Show Enhanced Expression of CB1-5HT2A Receptor Heteromers in Olfactory Neuroepithelium Cells