This is a vital paper, as it clearly outlines that ongoing opiate use ages the users faster than the non-drug using population; even more so in women who are seven times more susceptible to this process . The evidence also impugns the benign nature of long term Opiate Substitute Treatments.
Conclusion:
Data show that lifetime opioid exposure, an interactive cardiovascular risk factor, particularly in women, is related to linear, quadratic, cubic and quartic functions of treatment duration and is consistent with other literature of accelerated ageing in patients with Opiate Dependency.
